![]() We show that DNA methylation differs substantially between naïve and memory T cells, supporting the need for adjustment on these cell-types. Furthermore, we investigated whether these effects are mediated or not by changes in cellular composition, measured by deep immunophenotyping. ![]() Here, we assessed how the blood DNA methylome of 884 adults is affected by DNA sequence variation, age, sex and 139 factors relating to life habits and immunity. changes are required for normal development, yet the nature and respective contribution of factors that drive epigenetic variation in humans remain to be fully characterized. InitializeApplication(IntPtr appContext) 329 (IntPtr appContext, HttpContext context) 372 (HttpApplicationState state, MethodInfo handlers, IntPtr appContext, HttpContext context) 169 (IntPtr appContext, HttpContext context, MethodInfo handlers) 166 (HttpContext context, HttpApplication app) 535 Global.Application_Start(Object sender, EventArgs e) in d:\\bt\\932496\\repo\\src\\dev\\WebService\\:120 ThrottleClient.Initialize() in d:\\bt\\932496\\repo\\src\\dev\\Common\\Throttling\\ThrottleClient.cs:129 ThrottleClient.GetThrottleEndpoint() in d:\\bt\\932496\\repo\\src\\dev\\Common\\Throttling\\ThrottleClient.cs:577 (String identifier, TConfigItem
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